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Robert B. McWilliams, MD
Reproductive Endocrinology
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Baby Aspirin Before Conception

"What is all this about the need for low-dose, "Baby" aspirin before conception?" "Will it help me become pregnant?" "Will it decrease miscarriage rates?" "Are there any pregnancy risks if I take aspirin?"

Today, lots of questions are being asked by patients regarding the issue of the need for low-dose aspirin prior to conception. We would like to inform you of recent studies concerning this issue.

Over the past decade, numerous studies have supported the finding that daily maternal treatment with low-dose aspirin is associated with 1) a significant reduction in preeclampsia in pregnancy, 2) less fetal growth restriction, 3) a higher birth weight, 4) a reduction in preterm delivery, and 5) a reduction in the rate of miscarriage.

Implantation failure or early postimplantation loss has always been blamed as a leading cause of failure in ART (IVF, GIFT) cycles. Screening for the presence of autoimmune antibodies is recommended by many IVF centers while other centers recommend empiric treatment with low-dose aspirin and heparin.
With this information, we now recommend a single baby aspirin daily for all women trying to conceive.

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